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教授
詹阳Yang Zhan

神经生物学系长聘教研正教授

个人邮箱:

大道行思,取则行远

个人主页
研究领域

运用交叉学科方法解析大脑信息处理机制,研发新型脑机交互技术,探索神经疾病病理机制并开发创新性神经调控治疗策略。


个人简介

詹阳,深圳理工大学长聘教研正教授、博士生导师。专注于大脑神经信息处理与脑机交互研究。2003年本科毕业于大连理工大学,2010年获剑桥大学博士学位,后获欧盟玛丽居里基金资助在欧洲分子生物学实验室(EMBL)从事博士后研究。2014年加入中国科学院深圳先进技术研究院,任研究员、脑智能中心主任。获得中国科学院人才计划,科技部重点研发计划,广东省珠江人才团队项目,国家自然科学基金委等项目资助。


学习工作经历

学习经历

2006-2010 剑桥大学,博士

2003-2005  约克大学,电子学,硕士

1999-2003 大连理工大学,电子信息工程, 学士


工作经历

中国科学院深圳先进技术研究院,研究员

欧洲分子生物实验室,博士后


学术成果

国际影响力

第六届中德前沿会议主席

第七届中德前沿科学会议组委会委员

Nature 学术会议情感神经环路会议组委会委员

2019中国生物医学工程大会康复工程技术前沿与产业创新分会特邀报告

2020 深圳人工智能技术前沿高峰论坛特邀报告

担任多个国际期刊的论文审稿人


所获荣誉

深圳市海外高层次人才


科研成果

研究成果发表于Neuron、Nature Neuroscience、Nature Communications、IEEE Trans等高水平期刊,被Nature、Science、Nature Reviews Neuroscience等杂志正面引用。授权专利30余项,部分技术实现产业转化,并开展临床数据采集与算法测试。


代表性文章

2025

(1) Liu Q, Ouyang Y, Wang Y, Zhou S, Zhan Y*, Wang L*. Multianalyte Nanopore Detection of Alzheimer's Disease Biomarkers: A Label-Free Platform with Improved Sensitivity and Range. Adv Healthc Mater. 2025, e2405058. doi: 10.1002/adhm.202405058

2024

(1) Zheng X, Zhou F, Fu M, Xu L, Wang J, Li J, Li K, Sindermann C, Montag C, Becker B, Zhan Y*, Kendrick KM*. Patterns of neural activity in response to threatening faces are predictive of autistic traits: modulatory effects of oxytocin receptor genotype. Transl Psychiatry. 2024. 14(1):168. doi: 10.1038/s41398-024-02889-w.

(2) Zhong T, Jin X, Long Z, Lin Y, Liang S, Lin R, Tang Y, Xing L, Yan Xie Y*, Zhan Y*, Xue X*, A solar-powered self-clean gas-sensing neural modulator for behavioral intervention with spatiotemporal flexibility, Nano Energy. 2024, 124, 109518. doi: 10.1016/j.nanoen.2024.109518.

(3) Chen Z, Han Y, Ma Z, Wang X, Xu S, Tang Y, Vyssotski AL, Si B, Zhan Y*. A prefrontal-thalamic circuit encodes social information for social recognition. Nat Commun. 2024. 15: 1036. doi: 10.1038/s41467-024-45376-y.

(4) Zhong T, Yi H, Gou J, Li J, Liu M, Gao X, Chen S, Guan H, Liang S, He Q, Lin R, Long Z, Wang Y, Shi C, Zhan Y, Zhang Y, Xing L, Zhong J*, Xue X*. A wireless battery-free eye modulation patch for high myopia therapy. Nat Commun. 2024. 15: 1766. doi: 10.1038/s41467-024-46049-6.

(5) Lv Z, Chen L, Chen P, Peng H, Rong Y, Hong W, Zhou Q, Li N, Li B, Paolicelli RC, Zhan Y*. Clearance of β-amyloid and synapses by the optogenetic depolarization of microglia is complement selective. Neuron. 2024, 112: 740-754.e7. doi: 10.1016/j.neuron.2023.12.003.

(6) Shan Liang, Dongming Li, Rui Lin, Zhixin Yang, Guangyou Yang, Tianyan Zhong, Yong Tang, Mingwang Zhang, Zhen Wang, Han Bao, Pingjin Zou, Meihua Chen, Bin Tang, Lili Xing, Xinyu Xue*, Zhan Y*, Yan Xie*, A battery-free anti-inflammatory brain remote for spatiotemporal guiding movement of mice, Applied Materials Today 2024, 37 102141. doi: 10.1016/j.apmt.2024.102141.

2023

(1) Dou Y, Xia J, Fu M, Cai Y, Meng X*, Zhan Y*. Identification of epileptic networks with graph convolutional network incorporating oscillatory activities and evoked synaptic responses. NeuroImage. 2023: 284:120439. doi: 10.1016/j.neuroimage.2023.120439.

(2) Zhang M, Yang G, Long Z, Tang Y, Li D, Liang S, Lin R, Yang Z, Bao H, Xing L, Xue X*, Zhan Y*, Xie Y*, Wireless Battery-Free Peripheral Nerve Stimulation Conch for Remote Muscle Activation. Adv. Mater. Technol. 2023, 2301458. doi: 10.1002/admt.202301458.

(3) Guan H, Tang Y, Long Z, Lin R, Liang S, Zhu F, Zhong T, Zhang Y, Fan Y, Wang Z, Shi C, Ma W, Sun S, Chen M, Xing L, Zhang Y*, Xue X*, Zhan Y*. Cellphone remote intelligent neuroregulation with self-powered piezoelectric wireless brain probe. Nano Energy. 2023, 106:108105. doi: 10.1016/j.nanoen.2022.108105.

(4) Lin R, Fan Y, Xie Y, Ge D, Liang S, Guan H, Chen M, Zhang Y, Xing L*, Xue X*,Zhan Y*. A self-powered wearable seizure-monitoring/brain-stimulating system for potential epilepsy treatment. Nano Energy. 2023, 107:108121. doi: 10.1016/j.nanoen.2022.108121.

(5) Wang X, Tang R, Wei Z, Zhan Y, Lu J*, Li Z*. The enteric nervous system deficits in autism spectrum disorder. Front Neurosci. 2023. 17: 1101071. doi: 10.3389/fnins.2023.1101071.

(6) Yang L, Shen J, Liu C, Kuang Z, Tang Y, Qian Z, Guan M, Yang Y, Zhan Y, Li N, Li X*. Nicotine rebalances NAD+ homeostasis and improves aging-related symptoms in male mice by enhancing NAMPT activity. Nat Commun. 2023, 14(1):900. doi: 10.1038/s41467-023-36543-8. PMID: 36797299

2022

(1) Xu C, Xie Y, Zhong T, Liang S, Guan H, Long Z, Cao H, Xing L*, Xue X*, Zhan Y*. A self-powered wearable brain-machine-interface system for real-time monitoring and regulating body temperature. Nanoscale. 2022, 14, 12483-12490. doi: 10.1039/d2nr03115a.

(2) Xie J, Zhang J, Sun J, Ma Z, Qin L, Li G, Zhou H*, Zhan Y*. A Transformer-Based Approach Combining Deep Learning Network and Spatial-Temporal Information for Raw EEG Classification. IEEE Trans Neural Syst Rehabil Eng. 2022, 30:2126-2136. doi: 10.1109/TNSRE.2022.3194600.

(3) Geng Y, Qin L, Li Y, Yu Z, Li L, Asogbon MG, Zhan Y, Yan N, Guo X, Li G*. Identifying oscillations under multi-site sensory stimulation for high-level peripheral nerve injured patients: a pilot study. J Neural Eng. 2022 Jun 6;19(3). doi: 10.1088/1741-2552/ac7079.

(4) Luo W, Yun D, Hu Y, Tian M, Yang J, Xu Y, Tang Y, Zhan Y, Xie H, Guan JS*. Acquiring new memories in neocortex of hippocampal-lesioned mice. Nat Commun. 2022, 13, 1601. DOI: 10.1038/s41467-022-29208-5

(5) Gao Y, Xia X, Liu L, Wu T, Chen T, Yu J, Xu Z, Wang L, Yan F, Du Z, Chu J, Zhan Y, Peng B, Li H*, Zheng W*. Axial gradient excitation accelerates volumetric imaging of two-photon microscopy. Photon. Res. 2022. 10, 687-696. DOI: 10.1364/PRJ.441778.

(6) Xiang W, Xie Y, Han Y, Long Z, Zhang W, Zhong T, Liang S, Xing L*, Xue X*, Zhan Y*. A self-powered wearable brain-machine-interface system for ceasing action. Nanoscale. 2022,14, 4671-4678. DOI:10.1039/d1nr08168c.

(7) Liang S, Han Y, Zhang W, Zhong T, Guan H, Song Y, Zhang Y, Xing L, Xue X*, Li G*, Zhan Y*. A self-powered wearable body-detecting/brain-stimulating system for improving sports endurance performance. Nano Energy. 2022, 93, 106851. DOI: 10.1016/j.nanoen.2021.106851.

(8) Yang G, Tang Y, Lin T, Zhong T, Fan Y, Zhang Y, Xing L*, Xue X*, Zhan Y*. A self-powered closed-loop brain-machine-interface system for real-time detecting and rapidly adjusting blood glucose concentration. Nano Energy. 2022, 93, 106817. DOI: 10.1016/j.nanoen.2021.106817.

(9) Xiang W, Xie Y, Han Y, Long Z, Zhang W, Zhong T, Liang S, Xing L*, Xue X*, Zhan Y*. A self-powered wearable brain-machine-interface system for ceasing action. Nanoscale. 2022.14, 4671-4678. doi: 10.1039/d1nr08168c

(10) Wang S, Chen H, Zhan Y*. Novel Causal Relations between Neuronal Networks due to Synchronization. Cerebral Cortex. 2022, 32(2): 429-438. DOI: doi.org/10.1093/cercor/bhab219. [

2021

(1) Schilling KG et al., Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset? NeuroImage. 2021, 243, 118502. DOI: 10.1016/j.neuroimage.2021.118502.

(2) Dong W, Chen H, Sit T, Han Y, Song F, Vyssotski AL, Gross CT, Si B*, Zhan Y*. Characterization of exploratory patterns and hippocampal–prefrontal network oscillations during the emergence of free exploration. Science Bulletin. 2021, 66: 2238-2250. DOI: 10.1016/j.scib.2021.05.018.

(3)Zhao T, Han Y, Qin L, Guan H, Xing L, Li X, Xue X*, Li G*, Zhan Y*. Bidirectional modulation of neural plasticity by self-powered neural stimulation. Nano Energy. 2021, 85, 106006. DOI: 10.1016/j.nanoen.2021.106006.

2020

(1) Guan H, Lv D, Zhong T, Dai Y, Xing L, Xue X*, Zhang Y*, Zhan Y*, Self-powered, wireless-control, neural-stimulating electronic skin for in vivo characterization of synaptic plasticity. Nano Energy. 2020, 67, 104182. DOI: 10.1016/j.nanoen.2019.104182.

2019

(1) Zhong T, Zhang M, Fu Y, Han Y, Guan H, He H, Zhao T, Xing L, Xue X*, Zhang Y*, Zhan Y*, An artificial triboelectricity-brain-behavior closed loop for intelligent olfactory substitution. Nano Energy. 2019, 63, 103884. DOI: 10.1016/j.nanoen.2019.103884.

2018

(1) Zeng H, He H, Fu Y, Zhao T, Han W, Xing L, Zhang Y*, Zhan Y*, Xue X*, A self-powered brain-linked biosensing electronic-skin for actively tasting beverage and its potential application in artificial gustation. Nanoscale. 2018. DOI: 10.1039/c8nr06178e.

(2) Dai XJ, Jiang J, Zhang Z, Nie X, Liu BX, Pei L, Gong H, Hu J, Lu G*, Zhan Y*. Plasticity and Susceptibility of Brain Morphometry Alterations to Insufficient Sleep. Front Psychiatry. 2018, 9:266. DOI: 10.3389/fpsyt.2018.00266.

(3) Dai Y, Fu Y, Zeng H, Xing L, Zhang Y*, Zhan Y*, Xue X*. A Self-Powered Brain-Linked Vision Electronic-Skin Based on Triboelectric-Photodetecing Pixel-Addressable Matrix for Visual Image Recognition and Behavior Intervention. Advanced Functional Materials. 2018, 28, 1800275. DOI: 10.1002/adfm.201800275.

(4) Fu Y, Zhang M, Dai Y, Zeng H, Sun C, Han Y, Xing L, Wang S, Xue X*, Zhan Y*, Zhang Y*, A self-powered brain multi-perception receptor for sensory-substitution application. Nano Energy. 2018, 44: 43–52. DOI: 10.1016/j.nanoen.2017.11.068.

2017

(1) Zhou TT, Zhu H, Fan ZX, Wang F, Chen Y, Liang HX, Yang ZF, Zhang L, Lin LN, Zhan Y, Wang Z, Hu H*. History of winning remodels thalamo-PFC circuit to reinforce social dominance. Science. 2017, 357: 162-168. DOI: 10.1126/science.aak9726.

(2) Franklin TB, Silva BA, Perova Z, Marrone L, Masferrer ME, Zhan Y, Kaplan A, Greetham L, Verrechia V, Halman A, Pagella S, Vyssotski AL, Illarionova A, Grinevich V, Branco T, Gross CT*. Prefrontal cortical control of a brainstem social behavior circuit. Nature Neurosci. 2017, 20(2):260-270. DOI: 10.1038/nn.4470.

2016

(1) Zhan Y*. Harnessing GABAergic Transmission for Slow Oscillations. Neurosci Bull. 2016, 32(5): 501-502. DOI: 10.1007/s12264-016-0058-1.

(2) Song W, Xu Q, Zhang Y, Zhan Y, Zheng W*, Song L*. Fully integrated reflection-mode photoacoustic, two-photon, and second harmonic generation microscopy in vivo, Sci Rep. 2016, 6: 32240. DOI: 10.1038/srep32240.

(3) Lu Y, Zhong C, Wang L, Wei P, He W, Huang K, Zhang Y, Zhan Y, Feng G, Wang L*. Optogenetic dissection of ictal propagation in the hippocampal-entorhinal cortex structures. Nat Commun. 2016, 7:10962. DOI: 10.1038/ncomms10962.

(4) Dai XJ, Nie X, Liu X, Pei L, Jiang J, Peng DC, Gong HH*, Zeng XJ*, Wáng YJ, Zhan Y, Gender Differences in Regional Brain Activity in Patients with Chronic Primary Insomnia: Evidence from a Resting-State fMRI Study. J Clin Sleep Med. 2016, 12(3): 363–374. DOI: 10.5664/jcsm.5586.

2015

(1) Zhan Y*. Theta frequency prefrontal hippocampal driving relationship during free exploration in mice, Neuroscience, 2015, 300:554 565. DOI: 10.1016/j.neuroscience.2015.05.063.

2014

(1) Amendola E, Zhan Y, Mattucci C, Castroflorio E, Calcagno E, Fuchs C, Lonetti G, Silingardi D, Farley D, Ciani E, Pizzorusso T, Giustetto M, Gross C*. Mapping pathological phenotypes in a mouse model of CDKL5 disorder. PLoS ONE. 2014, 9(5), e91613. DOI: 10.1371/journal.pone.0091613.

(2) Zhan Y, Paolicelli RC, Gozzi, A, Pagani F, Gozzi A, Vyssotski A, Bifone A, Ragozzino D, and Gross C*. Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior, Nature Neurosci. 2014,17(3): 400-406. DOI: 10.1038/nn.3641.



英文名 Yang Zhan 首字母 Z
学系 神经生物学系 岗位 教授
职称-职务 神经生物学系长聘教研正教授 前海外职称-职务 欧洲分子生物实验室博士后
邮箱 座右铭 大道行思,取则行远
介绍一 介绍二
个人主页 https://yangZhanLab.lhs.suat-sz.edu.cn/