Selected publications
1.Spatial multi-omics at subcellular resolution via high-throughput in situ pairwise sequencing. Xiaofeng Wu#, Weize Xu#, Lulu Deng, Yue Li, Zhongchao Wang, Leqiang Sun, Anran Gao, Haoqi Wang, Xiaodan Yang, Chengchao Wu, Yanyan Zou, Keji Yan, Zhixiang Liu, Lingkai Zhang, Guohua Du, Liyao Yang, Da Lin, Ping Wang, Yunyun Han, Zhenfang Fu, Jinxia Dai*, Gang Cao*, Nature Biomedical Engineering. 2024
2.MGA-seq: robust identification of extrachromosomal DNA and genetic variants using multiple genetic abnormality sequencing. Da Lin*#, Yanyan Zou#, Xinyu Li, Jinyue Wang, Qin Xiao, Xiaochen Gao, Fei Lin, Ningyuan Zhang, Ming Jiao, Yu Guo, Zhaowei Teng, Shiyi Li, Yongchang Wei, Fuling Zhou, Rong Yin, Siheng Zhang, Lingyu Xing, Weize Xu, Xiaofeng Wu, Bing Yang, Ke Xiao, Chengchao Wu, Yingfeng Tao, Xiaoqing Yang, Jing Zhang, Sheng Hu, Shuang Dong, Xiaoyu Li, Shengwei Ye, Zhidan Hong, Yihang Pan, Yuqin Yang, Haixiang Sun*, Gang Cao*. Genome Biology, 2023
3.Highly efficient and robust π-FISH rainbow for multiplexed in situ detection of diverse biomolecules. Tao Y#, Zhou X#, Sun L, Lin D, Cai H, Chen X, Zhou W, Yang B, Hu Z, Yu J, Zhang J, Yang X, Yang F, Shen B, Qi W, Fu Z, Dai J*, Cao G*. Nature Communications. 2023 (Featured article)
4.Decoding the spatial chromatin organization and dynamic epigenetic landscapes of macrophage cells during differentiation and immune activation. Lin D#, Xu W#, Hong P#, Wu C, Zhang Z, Zhang S, Xing L, Yang B, Zhou W, Xiao Q, Wang J, Wang C, He Y, Chen X, Cao X, Man J, Reheman A, Wu X, Hao X, Hu Z, Chen C, Cao Z, Yin R, Fu ZF, Zhou R, Teng Z, Li G*, Cao G*. Nature Communications. 2022
5.Neuron-derived neuropeptide Y fine-tunes the splenic immune responses. Yu J#, Xiao K#, Chen X, Deng L, Zhang L, Li Y, Gao A, Gao J, Wu C, Yang X, Zhou Q, Yang J, Bao C, Jiao J, Cheng S, Guo Z, Xu W, Cao X, Guo Z, Dai J, Hu J, Fu Z, Cao G*. Neuron. 2022 (Highlight article)
6.Reprogramming Mycobacterium tuberculosis CRISPR System for Gene Editing and Genome-wide RNA Interference Screening. Rahman K#, Jamal M#, Chen X, Zhou W, Yang B, Zou Y, Xu W, Lei Y, Wu C, Cao X, Tyagi R, Naeem MA, Lin D, Habib Z, Peng N, Fu ZF*, Cao G*. Genomics Proteomics Bioinformatics. 2021
7.Strategies to package recombinant Adeno-Associated Virus expressing the N-terminal gasdermin domain for tumor treatment. Lu Y#, He W#, Huang X, He Y, Gou X, Liu X, Hu Z, Xu W, Rahman K, Li S, Hu S*, Luo J*, Cao G*. Nature Communications. 2021
8.Single-cell atlas of domestic pig cerebral cortex and hypothalamus. Zhu J#, Chen F#, Luo L#, Wu W#, Dai J#, Zhong J, Lin X, Chai C, Ding P, Liang L, Wang S, Ding X, Chen Y, Wang H, Qiu J, Wang F, Sun C, Zeng Y, Fang J, Jiang X, Liu P, Tang G, Qiu X, Zhang X, Ruan Y, Jiang S, Li J, Zhu S, Xu X, Li F, Liu Z, Cao G*, Chen D*. Science Bulletin. 2021 (Cover Story)
9.RUNX1-mediated alphaherpesvirus-host trans-species chromatin interaction promotes viral transcription. Xiao K#, Xiong D#, Chen G, Yu J, Li Y, Chen K, Zhang L, Xu Y, Xu Q, Huang X, Gao A, Cao K, Yan K, Dai J, Hu X, Ruan Y, Fu Z*, Li G*, Cao G*. Science Advances. 2021
10.Differences in neurotropism and neurotoxicity among retrograde viral tracers. Sun L#, Tang Y#, Yan K, Yu J, Zou Y, Xu W, Xiao K, Zhang Z, Li W, Wu B, Hu Z, Chen K, Fu ZF, Dai J*, Cao G*. Mol Neurodegener. 2019
11.Digestion-ligation-only Hi-C is an efficient and cost-effective method for chromosome conformation capture. Lin D#, Hong P#, Zhang S, Xu W, Jamal M, Yan K, Lei Y, Li L, Ruan Y, Fu ZF, Li G*, Cao G*. Nature Genetics. 2018 (Highlight article)
12.Development and application of a recombination-based library versus library high- throughput yeast two-hybrid (RLL-Y2H) screening system. Yang F#, Lei Y#, Zhou M, Yao Q, Han Y, Wu X, Zhong W, Zhu C, Xu W, Tao R, Chen X, Lin D, Rahman K, Tyagi R, Habib Z, Xiao S, Wang D, Yu Y, Chen H, Fu Z, Cao G*. Nuclear Acid Research. 2018
13.Distinct persistence fate of Mycobacterium tuberculosis in various types of cells. Xi Chen#, Xiaojian Cao#, Yingying Lei#, Aikebaier Rehman, Wei Zhou, Bing Yang, Weipan Zhang, Weize Xu, Shuang Dong, Rohit Tyagi, Zhen F. Fu*, Gang Cao*. mSystem, 2021
14.Delineating the Organization of Projection Neuron Subsets with Multi-fluorescent Rabies Virus Tracing Tool.Liang Li#, Yajie Tang#, Leqiang Sun,Jinsong Yu, Jinxia Dai*; Gang Cao*. Brain Structure and Function. 2021
15.Screening of Compounds for Anti-tuberculosis Activity, and In Vitro and In Vivo Evaluation of Potential Candidates. Wei Zhou#, Bing Yang#, Yanyan Zou, Khaista Rahman, Xiaojian Cao, Yingying Lei, Ren Lai, Zhen F Fu, Xi Chen*, Gang Cao*. Frontiers in Microbiology. 2021
16.Rv3722c Promotes Mycobacterium tuberculosis Survival in Macrophages by Interacting With TRAF3. Yingying Lei, Xiaojian Cao, Weize Xu, Bing Yang, Yangyang Xu, Wei Zhou, Shuang Dong, Qijun Wu, Khaista Rahman, Rohit Tyagi, Shuhong Zhao, Chen X*, and Cao G*. Front Cell Infect Microbiol. 2021
17.Fiber photometry of neural activity in specific neural circuit. Jinsong Yu, Yue Li, Mona N Hussein, Zhongchao Wang, Jinxia Dai*, Gang Cao*. Springer Nature, Book chapter, 2020
18.Robust capturing chromosome conformation using the DLO Hi-C 2.0 method. Zhang Z, Wu C, Rahman K, Xu W, Li G*, Lin D*, Cao G*. J Genet Genomics. 2020
19.The DLO Hi-C Tool for Digestion-Ligation-Only Hi-C Chromosome Conformation Capture Data Analysis. Hong P#, Jiang H#, Xu W#, Lin D#, Xu Q, Cao G*, Li G*. Genes (Basel). 2020
20.The anatomy and metabolome of the lymphatic system in the brain in health and disease. He W, Jing Y, Wan Q, Xiao K, Chen K, Lu Y, Li L, Tang Y, Deng Y*, Yao Z*, Yue J*, Cao G*. Brain Pathol. 2020
21.Rapid Bacteria Identification using Structured Illumination Microscopy and Machine Learning. He Y#, Xu W#, Zhi Y#, Tyagi R, Hu Z#, Cao G#. Journal of Innovative Optical Health Science. 2018
22.Optogenetic Modulation of Cardiac Sympathetic Nerve Activity to Protect Against Ventricular Arrhythmias: A Proof-of-Concept Study. Yu L#, Zhou L#, Cao G#, S. Po S, Huang B, Zhou X, Wang M, Yuan S, Wang Z,Wang S, Jiang H*. JACC, 2017 (Highlight article)
23.In vivo fiber photometry of neural activity in response to optogenetically manipulated inputs in freely moving mice. Li L, Tang Y, Sun L, Khaista R, Huang K, Xu W, Yu J, Dai J*, Cao G*. Journal of Innovative Optical Health Science. 2017
24.Adaptive Gene Profiling of Mycobacterium Tuberculosis during Sub-lethal Kanamycin Exposure. Habib Z#, Xu W#, Jamal M, Rehman K, Dai J, Fu Z, Chen X*, Cao G*. Microbial pathogenesis. 2017.
25.Rabies viruses leader RNA interacts with host Hsc70 and inhibits virus replication. Zhang R, Liu C, Cao Y, Jamal M, Chen X, Zheng J, Li L, You J, Zhu Q, Liu S, Dai J, Cui M, Fu ZF*, Cao G*. Oncotaget. 2017
26.Mycobacteria and Autophagy: Many Questions and Few Answers. Liang M, Habib Z, Sakamoto K, Chen X, Cao G*. Curr Issues Mol Biol. 2017
27.A CRISPR/Cas9 and Cre/Lox system-based express vaccine development strategy against re-emerging Pseudorabies virus, Liang X#, Sun L#, Yu T#, Pang Y, Hu Q, Fu Z, He Q*, Cao G*, Scientific Report, 2016
28.Keeping CRISPR/Cas on-Target. Jamal M, Khan F, Lin D, Habib Z, Dai J*, Cao G*. Curr Issues Mol Biol. 2016